Reviewed By
Overview
SCIENTIFIC SCORE
Possibly Effective
Based on 35 Researches
7.1
USERS' SCORE
Moderately Good
Based on 52 Reviews
7.8
Supplement Facts
Serving Size: 1 Softgel
Amount Per Serving
%DV
Calories
10
Total Fat
1 g
1%*
Polyunsaturated Fat
1 g
†
Fish Oil Concentrate
1 g (1,000 mg)
†
Docosahexaenoic Acid (DHA)
500 mg
†
Eicosapentaenoic Acid (EPA)
250 mg
†
Top Medical Research Studies
9
We examined how different doses and durations of omega-3 fatty acids (PUFAs) affect heart failure management. Our study analyzed data from 14 randomized controlled trials, involving nearly 9,100 participants. We found that high doses of omega-3 (2000-4000 mg daily) for at least a year significantly improved heart function, particularly left ventricular ejection fraction and peak oxygen consumption. However, lower doses and shorter durations didn't yield the same benefits, and no increased risk of adverse events was noted. More research is needed to solidify these results.
Read More
9
We explored the relationship between fish oil supplements and heart health in over 20,000 individuals with type 2 diabetes. The study found that regular fish oil use and higher levels of DHA, a type of omega-3 fatty acid, were linked to a lower risk of serious complications like heart disease and kidney issues.
Specifically, those with elevated DHA levels experienced significant reductions in the risk of macrovascular and microvascular complications. These positive outcomes were partially attributed to improvements in lipid profiles and inflammation.
This research highlights the potential benefits of incorporating DHA into our diets for better heart health.
Specifically, those with elevated DHA levels experienced significant reductions in the risk of macrovascular and microvascular complications. These positive outcomes were partially attributed to improvements in lipid profiles and inflammation.
This research highlights the potential benefits of incorporating DHA into our diets for better heart health.
Read More
9
We examined the connection between omega-3 polyunsaturated fatty acid (PUFA) levels and coronary heart disease (CHD). By analyzing 36 relevant studies, we observed that higher omega-3 levels, including DHA, were linked to a lower risk of developing CHD.
The analysis revealed significant reductions in risk, with particularly strong associations for patients with fatal and non-fatal CHD. Overall, our findings suggest that boosting omega-3 intake could be beneficial for heart health.
The analysis revealed significant reductions in risk, with particularly strong associations for patients with fatal and non-fatal CHD. Overall, our findings suggest that boosting omega-3 intake could be beneficial for heart health.
Read More
Most Useful Reviews
7.5
Supports heart health
241 people found this helpful
Natural and helpful. It's a great supplement, especially for those with memory issues or high cholesterol. The dosage is significant for older individuals needing preventive care. My relative was prescribed this after a heart attack, and it has greatly supported their recovery.
Read More
9
Improves heart health
107 people found this helpful
Best! This fish oil has improved my skin significantly at 56. Despite being on HRT for years, my skin was fading. This supplement has rejuvenated it. My sister noticed stronger hair too. It also supports cardiovascular health, aids migraines, and reduces headaches. I recommend consulting a doctor first.
Read More
9
Reduces heart disease risks
63 people found this helpful
Omega-3 consists of EPA, which has a potent anti-inflammatory effect, lowering heart disease, cardiovascular issues, and even some cancers. DHA supports brain health. This supplement is crucial for heart and vascular health.
Read More
Medical Researches
SCIENTIFIC SCORE
Possibly Effective
Based on 35 Researches
7.1
- All Researches
9
We examined how different doses and durations of omega-3 fatty acids (PUFAs) affect heart failure management. Our study analyzed data from 14 randomized controlled trials, involving nearly 9,100 participants. We found that high doses of omega-3 (2000-4000 mg daily) for at least a year significantly improved heart function, particularly left ventricular ejection fraction and peak oxygen consumption. However, lower doses and shorter durations didn't yield the same benefits, and no increased risk of adverse events was noted. More research is needed to solidify these results.
Read More
9
We explored the relationship between fish oil supplements and heart health in over 20,000 individuals with type 2 diabetes. The study found that regular fish oil use and higher levels of DHA, a type of omega-3 fatty acid, were linked to a lower risk of serious complications like heart disease and kidney issues.
Specifically, those with elevated DHA levels experienced significant reductions in the risk of macrovascular and microvascular complications. These positive outcomes were partially attributed to improvements in lipid profiles and inflammation.
This research highlights the potential benefits of incorporating DHA into our diets for better heart health.
Specifically, those with elevated DHA levels experienced significant reductions in the risk of macrovascular and microvascular complications. These positive outcomes were partially attributed to improvements in lipid profiles and inflammation.
This research highlights the potential benefits of incorporating DHA into our diets for better heart health.
Read More
9
We examined the connection between omega-3 polyunsaturated fatty acid (PUFA) levels and coronary heart disease (CHD). By analyzing 36 relevant studies, we observed that higher omega-3 levels, including DHA, were linked to a lower risk of developing CHD.
The analysis revealed significant reductions in risk, with particularly strong associations for patients with fatal and non-fatal CHD. Overall, our findings suggest that boosting omega-3 intake could be beneficial for heart health.
The analysis revealed significant reductions in risk, with particularly strong associations for patients with fatal and non-fatal CHD. Overall, our findings suggest that boosting omega-3 intake could be beneficial for heart health.
Read More
9
We explored how docosahexaenoic acid (DHA), a type of omega-3 fatty acid, might help reduce the risk of heart disease, specifically sudden cardiac death (SCD) and cardiovascular mortality. Our investigation drew on data from ten prospective cohort studies involving over 310,000 participants and covered an average follow-up of nearly nine years.
The results were promising. We observed that higher levels of omega-3 fatty acids, including DHA, in the blood were associated with a lower risk of adverse heart events. Specifically, individuals with elevated levels of DHA displayed a notable reduced risk for both SCD and overall cardiovascular mortality when compared to those with lower levels.
This correlation highlights DHA's potential role in heart health, making it an important focus for anyone looking to improve their cardiovascular wellness. Our findings suggest that increasing DHA intake could serve as a proactive step in protecting against serious heart conditions.
The results were promising. We observed that higher levels of omega-3 fatty acids, including DHA, in the blood were associated with a lower risk of adverse heart events. Specifically, individuals with elevated levels of DHA displayed a notable reduced risk for both SCD and overall cardiovascular mortality when compared to those with lower levels.
This correlation highlights DHA's potential role in heart health, making it an important focus for anyone looking to improve their cardiovascular wellness. Our findings suggest that increasing DHA intake could serve as a proactive step in protecting against serious heart conditions.
Read More
9
We explored the impact of diet enriched with docosahexaenoic acid (DHA) on combating cardiomyopathy syndrome (CMS) in farmed Atlantic salmon. This condition is a serious concern, especially during the seawater phase, where it leads to substantial mortality rates.
In our field study, we focused on a commercial sea farm experiencing a severe outbreak of CMS. We implemented a clinical nutrition intervention that included both eicosapentaenoic acid (EPA) and DHA, aiming to see how these changes would affect the health of the salmon.
Following the introduction of this enriched diet, we observed a noticeable decline in mortality rates and a regression of the heart disease symptoms. Additionally, our analysis revealed a significant reduction in the viral load of the piscine myocarditis virus (PMCV), showcasing a connection between dietary fatty acids and fish health.
The heart samples taken from the fish displayed increased levels of both EPA and DHA, strengthening our belief that optimizing these fatty acids in the diet may be beneficial during severe CMS outbreaks. While we must pursue further research to confirm these findings, the results are promising and indicate that nutrition can play a crucial role in managing heart disease in Atlantic salmon.
In our field study, we focused on a commercial sea farm experiencing a severe outbreak of CMS. We implemented a clinical nutrition intervention that included both eicosapentaenoic acid (EPA) and DHA, aiming to see how these changes would affect the health of the salmon.
Following the introduction of this enriched diet, we observed a noticeable decline in mortality rates and a regression of the heart disease symptoms. Additionally, our analysis revealed a significant reduction in the viral load of the piscine myocarditis virus (PMCV), showcasing a connection between dietary fatty acids and fish health.
The heart samples taken from the fish displayed increased levels of both EPA and DHA, strengthening our belief that optimizing these fatty acids in the diet may be beneficial during severe CMS outbreaks. While we must pursue further research to confirm these findings, the results are promising and indicate that nutrition can play a crucial role in managing heart disease in Atlantic salmon.
Read More
User Reviews
USERS' SCORE
Moderately Good
Based on 52 Reviews
7.8
- All Reviews
- Positive Reviews
- Negative Reviews
7.5
Supports heart health
241 people found this helpful
Natural and helpful. It's a great supplement, especially for those with memory issues or high cholesterol. The dosage is significant for older individuals needing preventive care. My relative was prescribed this after a heart attack, and it has greatly supported their recovery.
Read More
9
Improves heart health
107 people found this helpful
Best! This fish oil has improved my skin significantly at 56. Despite being on HRT for years, my skin was fading. This supplement has rejuvenated it. My sister noticed stronger hair too. It also supports cardiovascular health, aids migraines, and reduces headaches. I recommend consulting a doctor first.
Read More
9
Reduces heart disease risks
63 people found this helpful
Omega-3 consists of EPA, which has a potent anti-inflammatory effect, lowering heart disease, cardiovascular issues, and even some cancers. DHA supports brain health. This supplement is crucial for heart and vascular health.
Read More
7.5
Supports cardiovascular health
36 people found this helpful
The dosage is excellent, containing omega acids in proper amounts. Positive effects include enhanced hormone secretion, improved metabolism, and better muscle growth, which ultimately aids cardiovascular health and reduces heart disease risk.
Read More
9
Corrected my heart issues
6 people found this helpful
This supplement was crucial for my heart health at 27. I initially thought my issues were from other vitamins, but discovered I lacked omega-3 fatty acids, leading to high cholesterol. Since taking omega-3, my heart sensations have ceased, and I feel much healthier now.
Read More
Frequently Asked Questions
9
Doctor recommended
2 people found this helpful
Dr. Oz recommends this for heart health, and after eight months, my CRP levels improved significantly. There’s no stomach discomfort or burping. This brand has truly made a difference for both my husband and me.
9
Corrected my heart issues
6 people found this helpful
This supplement was crucial for my heart health at 27. I initially thought my issues were from other vitamins, but discovered I lacked omega-3 fatty acids, leading to high cholesterol. Since taking omega-3, my heart sensations have ceased, and I feel much healthier now.
9
Improved memory
2 people found this helpful
An excellent omega product with great DHA! Taking two capsules daily lasts me three months. I've noticed improvements in my heart health, memory, and overall energy levels. My hair and skin have also improved significantly. Highly recommend!
9
Improves heart health
107 people found this helpful
Best! This fish oil has improved my skin significantly at 56. Despite being on HRT for years, my skin was fading. This supplement has rejuvenated it. My sister noticed stronger hair too. It also supports cardiovascular health, aids migraines, and reduces headaches. I recommend consulting a doctor first.
9
Joint pain relief
5 people found this helpful
Recommended by my doctor, this product alleviated my joint and back pain within weeks. It benefits brain, heart, and eye health, and I've found it superior for inflammation compared to pharmaceuticals. Highly recommended.
7.5
Supports heart health
241 people found this helpful
Natural and helpful. It's a great supplement, especially for those with memory issues or high cholesterol. The dosage is significant for older individuals needing preventive care. My relative was prescribed this after a heart attack, and it has greatly supported their recovery.
9
Reduces heart disease risks
63 people found this helpful
Omega-3 consists of EPA, which has a potent anti-inflammatory effect, lowering heart disease, cardiovascular issues, and even some cancers. DHA supports brain health. This supplement is crucial for heart and vascular health.
9
Heart disease prevention
3 people found this helpful
Omega-3 fatty acids are essential for overall wellbeing and heart health. They lower bad cholesterol, reduce heart disease risks, combat joint inflammation, and enhance mental health. The benefits are numerous, making it a valuable addition to my diet.
We investigated how eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) supplementation affects coronary artery calcium (CAC) scores in people with coronary artery disease, particularly focusing on those with diabetes.
Over 30 months, we found that individuals with diabetes who took EPA and DHA experienced a greater increase in CAC scores compared to those with diabetes who did not receive the supplement.
However, no significant change was observed among those without diabetes. This insight into the relationship between DHA and heart disease could guide future treatments.
Over 30 months, we found that individuals with diabetes who took EPA and DHA experienced a greater increase in CAC scores compared to those with diabetes who did not receive the supplement.
However, no significant change was observed among those without diabetes. This insight into the relationship between DHA and heart disease could guide future treatments.
8
We explored the impact of omega-3 fatty acids, particularly docosahexaenoic acid (DHA), on heart disease via the large-scale VITAL study. This trial involved over 25,000 older adults in the U.S. who were monitored for about 5.3 years to assess how omega-3 FA supplementation influences cardiovascular events.
Although the findings from the VITAL trial indicated no significant results for major cardiovascular events, our analysis employing Bayesian methods suggested a different story. By incorporating previous research evidence, we found that daily supplementation of omega-3 fatty acids appears to significantly lower the risk of coronary events like heart attacks. However, it's important to note that this effect did not extend to reducing the risk of stroke.
Overall, this reevaluation supports the idea that omega-3 fatty acids, including DHA, could play a meaningful role in heart health, especially for preventing coronary-related issues. While the trial didn't show an impact on all aspects of heart disease, the results regarding coronary events provide valuable insights for the use of omega-3s in primary prevention strategies.
Although the findings from the VITAL trial indicated no significant results for major cardiovascular events, our analysis employing Bayesian methods suggested a different story. By incorporating previous research evidence, we found that daily supplementation of omega-3 fatty acids appears to significantly lower the risk of coronary events like heart attacks. However, it's important to note that this effect did not extend to reducing the risk of stroke.
Overall, this reevaluation supports the idea that omega-3 fatty acids, including DHA, could play a meaningful role in heart health, especially for preventing coronary-related issues. While the trial didn't show an impact on all aspects of heart disease, the results regarding coronary events provide valuable insights for the use of omega-3s in primary prevention strategies.
9
We examined the connection between omega-3 polyunsaturated fatty acid (PUFA) levels and coronary heart disease (CHD). By analyzing 36 relevant studies, we observed that higher omega-3 levels, including DHA, were linked to a lower risk of developing CHD.
The analysis revealed significant reductions in risk, with particularly strong associations for patients with fatal and non-fatal CHD. Overall, our findings suggest that boosting omega-3 intake could be beneficial for heart health.
The analysis revealed significant reductions in risk, with particularly strong associations for patients with fatal and non-fatal CHD. Overall, our findings suggest that boosting omega-3 intake could be beneficial for heart health.
7
We investigated how high doses of omega-3 fatty acids, specifically eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA), affect arterial inflammation in patients with increased lipoprotein(a) and stable coronary artery disease. In this small study, 12 participants took 3.6 g/day of omega-3s for 12 weeks.
We found that these fatty acids significantly lowered both triglyceride levels and arterial inflammation. Notably, the reduction in arterial inflammation was closely linked to EPA levels, while DHA did not show the same effect.
Thus, high doses of omega-3 fatty acids can help in reducing inflammation related to heart disease, specifically through the action of EPA.
We found that these fatty acids significantly lowered both triglyceride levels and arterial inflammation. Notably, the reduction in arterial inflammation was closely linked to EPA levels, while DHA did not show the same effect.
Thus, high doses of omega-3 fatty acids can help in reducing inflammation related to heart disease, specifically through the action of EPA.
9
We examined how different doses and durations of omega-3 fatty acids (PUFAs) affect heart failure management. Our study analyzed data from 14 randomized controlled trials, involving nearly 9,100 participants. We found that high doses of omega-3 (2000-4000 mg daily) for at least a year significantly improved heart function, particularly left ventricular ejection fraction and peak oxygen consumption. However, lower doses and shorter durations didn't yield the same benefits, and no increased risk of adverse events was noted. More research is needed to solidify these results.
8
Fatty acids' impact on heart disease
We investigated how different types of fatty acids relate to heart disease risk, using data from over 170,000 participants across three major studies. Our findings revealed that higher levels of total saturated fatty acids were linked to increased cardiovascular risk. Interestingly, docosahexaenoic acid (DHA) showed a protective effect against coronary heart disease. However, the evidence around other fatty acids was mixed, highlighting the need for further research, particularly randomized controlled trials, to clarify these associations.
9
We explored how docosahexaenoic acid (DHA), a type of omega-3 fatty acid, might help reduce the risk of heart disease, specifically sudden cardiac death (SCD) and cardiovascular mortality. Our investigation drew on data from ten prospective cohort studies involving over 310,000 participants and covered an average follow-up of nearly nine years.
The results were promising. We observed that higher levels of omega-3 fatty acids, including DHA, in the blood were associated with a lower risk of adverse heart events. Specifically, individuals with elevated levels of DHA displayed a notable reduced risk for both SCD and overall cardiovascular mortality when compared to those with lower levels.
This correlation highlights DHA's potential role in heart health, making it an important focus for anyone looking to improve their cardiovascular wellness. Our findings suggest that increasing DHA intake could serve as a proactive step in protecting against serious heart conditions.
The results were promising. We observed that higher levels of omega-3 fatty acids, including DHA, in the blood were associated with a lower risk of adverse heart events. Specifically, individuals with elevated levels of DHA displayed a notable reduced risk for both SCD and overall cardiovascular mortality when compared to those with lower levels.
This correlation highlights DHA's potential role in heart health, making it an important focus for anyone looking to improve their cardiovascular wellness. Our findings suggest that increasing DHA intake could serve as a proactive step in protecting against serious heart conditions.
References
- Liepinsh E, Gukalova B, Krims-Davis K, Kuka J, Leduskrasta A, et al. EPA and DHA acylcarnitines are less cardiotoxic than are saturated and monounsaturated long-chain acylcarnitines. Biofactors. 2025;51:e70014. 10.1002/biof.70014
- Grytten E, Laupsa-Borge J, Cetin K, Bohov P, Nordrehaug JE, et al. Inflammatory markers after supplementation with marine n-3 or plant n-6 PUFAs: A randomized double-blind crossover study. J Lipid Res. 2025;66:100770. 10.1016/j.jlr.2025.100770
- Tseng PT, Zeng BY, Hsu CW, Liang CS, Stubbs B, et al. The Optimal Dosage and Duration of ω-3 PUFA Supplementation in Heart Failure Management: Evidence from a Network Meta-Analysis. Adv Nutr. 2025;16:100366. 10.1016/j.advnut.2025.100366
- Lee YQ, Tan KH, Chong MF. Biomarkers of PUFA and cardiovascular risk factors and events in healthy Asian populations: a systematic review. Br J Nutr. 2024;132:1474. 10.1017/S0007114524002708
- Shi F, Chowdhury R, Sofianopoulou E, Koulman A, Sun L, et al. Association of circulating fatty acids with cardiovascular disease risk: analysis of individual-level data in three large prospective cohorts and updated meta-analysis. Eur J Prev Cardiol. 2025;32:233. 10.1093/eurjpc/zwae315
- Tian S, Guo T, Qian F, Qiu Z, Lu Q, et al. Fish Oil, Plasma n-3 PUFAs, and Risk of Macro- and Microvascular Complications among Individuals with Type 2 Diabetes. J Clin Endocrinol Metab. 2024. 10.1210/clinem/dgae482
- Xiao Y, Chen Y, Pietzner A, Elbelt U, Fan Z, et al. Circulating Omega-3 Polyunsaturated Fatty Acids Levels in Coronary Heart Disease: Pooled Analysis of 36 Observational Studies. Nutrients. 2024;16. 10.3390/nu16111610
- Asbeutah AA, Daher R, Malik A, Hariri E, Alfaddagh A, et al. The Effect of Eicosapentaenoic and Docosahexaenoic Acid Supplementation on Coronary Artery Calcium Progression in Subjects With Diabetes and Coronary Artery Disease: A Secondary Analysis of a Randomized Trial. Am J Cardiol. 2024;225:98. 10.1016/j.amjcard.2024.06.001
- Lin ZH, Xiang HQ, Yu YW, Xue YJ, Wu C, et al. Dihydroartemisinin alleviates doxorubicin-induced cardiotoxicity and ferroptosis by activating Nrf2 and regulating autophagy. FASEB J. 2024;38:e23677. 10.1096/fj.202400222RR
- Koh HB, Kim HW, Joo YS, Jung CY, Kim HJ, et al. Plasma Levels of Polyunsaturated Fatty Acids and Adverse Kidney Outcomes. Am J Kidney Dis. 2024;84:179. 10.1053/j.ajkd.2023.12.020
- Zeinalabedini M, Ladaninezhad M, Mobarakeh KA, Hoshiar-Rad A, Shekari S, et al. Association of dietary fats with ischemic heart disease (IHD): a case-control study. J Health Popul Nutr. 2024;43:19. 10.1186/s41043-023-00489-w
- Reiner MF, Bertschi DA, Werlen L, Wiencierz A, Aeschbacher S, et al. Omega-3 Fatty Acids and Markers of Thrombosis in Patients with Atrial Fibrillation. Nutrients. 2024;16. 10.3390/nu16020178
- Tang X, Lv X, Wang R, Li X, Xu W, et al. Association of marine PUFAs intakes with cardiovascular disease, all-cause mortality, and cardiovascular mortality in American adult male patients with dyslipidemia: the U.S. National Health and Nutrition Examination Survey, 2001 to 2016. Nutr J. 2023;22:48. 10.1186/s12937-023-00873-6
- Nakao K, Noguchi T, Miura H, Asaumi Y, Morita Y, et al. Effect of Eicosapentaenoic Acid/Docosahexaenoic Acid on Coronary High-Intensity Plaques Detected Using Noncontrast T1-weighted Imaging: The AQUAMARINE EPA/DHA Randomized Study. J Atheroscler Thromb. 2024;31:122. 10.5551/jat.64063
- Zhong N, Han P, Wang Y, Zheng C. Associations of polyunsaturated fatty acids with cardiovascular disease and mortality: a study of NHANES database in 2003-2018. BMC Endocr Disord. 2023;23:185. 10.1186/s12902-023-01412-4
- Ward NC, Ying Q, Chan DC, Pang J, Mori TA, et al. Improved arterial inflammation with high dose omega-3 fatty acids in patients with elevated lipoprotein(a): Selective effect of eicosapentaenoic acid?. J Clin Lipidol. 2023;17:694. 10.1016/j.jacl.2023.08.004
- Hamaya R, Cook NR, Sesso HD, Buring JE, Manson JE. A Bayesian Analysis of the VITAL Trial: Effects of Omega-3 Fatty Acid Supplementation on Cardiovascular Events. Am J Clin Nutr. 2025. 10.1016/j.ajcnut.2025.02.028
- Kim JY, Kong SYJ, Jung E, Cho YS. Omega-3 Fatty Acids as Potential Predictors of Sudden Cardiac Death and Cardiovascular Mortality: A Systematic Review and Meta-Analysis. J Clin Med. 2024;14. 10.3390/jcm14010026
- O'Keefe EL, O'Keefe JH, Abuissa H, Metzinger M, Murray E, et al. Omega-3 and Risk of atrial fibrillation: Vagally-mediated double-edged sword. Prog Cardiovasc Dis. 2024. 10.1016/j.pcad.2024.11.003
- Choi GY, Calder PC. The differential effects of eicosapentaenoic acid and docosahexaenoic acid on cardiovascular risk factors: an updated systematic review of randomized controlled trials. Front Nutr. 2024;11:1423228. 10.3389/fnut.2024.1423228
- Amangurbanova M, Daher R, Asbeutah AA, Vemuri B, Mirza H, et al. Higher epicardial adipose tissue volume is associated with higher coronary fatty plaque volume and is regulated by waist circumference but not EPA+DHA supplementation. J Clin Lipidol. 2024;18:e773. 10.1016/j.jacl.2024.06.006
- Lv L, Guo Y, Zheng Z, Li B. Blood metabolites mediate effects of breakfast skipping on heart failure via Mendelian randomization analysis. Sci Rep. 2024;14:18957. 10.1038/s41598-024-69874-7
- Wang Y, Yang B, Wang C. The association between fatty acids and atherosclerotic diseases: A mendelian randomization study. Clin Nutr ESPEN. 2024;63:447. 10.1016/j.clnesp.2024.06.018
- Dinu M, Sofi F, Lotti S, Colombini B, Mattioli AV, et al. Effects of omega-3 fatty acids on coronary revascularization and cardiovascular events: a meta-analysis. Eur J Prev Cardiol. 2024;31:1863. 10.1093/eurjpc/zwae184
- Braun TS, Drobner T, Kipp K, Kiehntopf M, Schlattmann P, et al. Validation of Nutritional Approaches to Modulate Cardiovascular and Diabetic Risk Factors in Patients with Hypertriglyceridemia or Prediabetes-The MoKaRi II Randomized Controlled Study. Nutrients. 2024;16. 10.3390/nu16091261
- O'Keefe EL, O'Keefe JH, Tintle NL, Westra J, Albuisson L, et al. Circulating Docosahexaenoic Acid and Risk of All-Cause and Cause-Specific Mortality. Mayo Clin Proc. 2024;99:534. 10.1016/j.mayocp.2023.11.026
- Rennemo J, Berge K, Yousaf MN, Eriksen TB, Welde E, et al. An Atypical Course of Cardiomyopathy Syndrome (CMS) in Farmed Atlantic Salmon () Fed a Clinical Nutrition Diet. Microorganisms. 2023;12. 10.3390/microorganisms12010026
- Aggarwal R, Bhatt DL, Steg PG, Miller M, Brinton EA, et al. Cardiovascular Outcomes With Icosapent Ethyl by Baseline Low-Density Lipoprotein Cholesterol: A Secondary Analysis of the REDUCE-IT Randomized Trial. J Am Heart Assoc. 2025;14:e038656. 10.1161/JAHA.124.038656
- Patil T, Gregory M, Savona N, Jarmukli N, Leonard CE. Evaluating the Real-World Safety of Icosapent Ethyl Versus Omega-3 Polyunsaturated Fatty Acid in Nationwide US Veterans Cohort: Examining Atrial Fibrillation and Bleeding Endpoints. Clin Drug Investig. 2025;45:69. 10.1007/s40261-024-01417-4
- Capece U, Gugliandolo S, Morciano C, Avolio A, Splendore A, et al. Erythrocyte Membrane Fluidity and Omega-3 Fatty Acid Intake: Current Outlook and Perspectives for a Novel, Nutritionally Modifiable Cardiovascular Risk Factor. Nutrients. 2024;16. 10.3390/nu16244318
- Fukuda T, Nakajima T, Hasegawa T, Amano H, Arikawa T, et al. Relationship Between Serum ω-3 Polyunsaturated Fatty Acid Concentration and Fatty Acid Fraction of Epicardial Adipose Tissue in Patients With Cardiovascular Disease. Cureus. 2024;16:e73417. 10.7759/cureus.73417
- Li J, Nan W, Huang X, Meng H, Wang S, et al. Eicosapentaenoic acid induces macrophage Mox polarization to prevent diabetic cardiomyopathy. EMBO Rep. 2024;25:5507. 10.1038/s44319-024-00271-x
- Kumakura H, Funada R, Matsuo Y, Iwasaki T, Nakashima K, et al. Eicosapentaenoic Acid Level Predicts Long-Term Survival and Cardiovascular or Limb Event in Peripheral Arterial Disease. Ann Vasc Dis. 2024;17:135. 10.3400/avd.oa.23-00079
- Sudo Y, Morimoto T, Tsushima R, Oka A, Sogo M, et al. Eicosapentaenoic Acid and the Outcomes in Older Patients Undergoing Atrial Fibrillation Ablation. J Am Heart Assoc. 2024;13:e033969. 10.1161/JAHA.123.033969
- Miyauchi K, Iwata H, Nishizaki Y, Inoue T, Hirayama A, et al. Randomized Trial for Evaluation in Secondary Prevention Efficacy of Combination Therapy-Statin and Eicosapentaenoic Acid (RESPECT-EPA). Circulation. 2024;150:425. 10.1161/CIRCULATIONAHA.123.065520
